Diagnostic Tools for Immunological and Virological Monitoring of HIV Infection
Diagnosis of HIV infection can be carried out by detecting any of the following test Antibodies to HIV, P24 HIV antigen and HIV nucleic acid (RNA/DNA). The most commonly used method for the diagnosis of HIV infection is detection of anti-HIV antibodies in serum/plasma. It is economical, rapid and can be performed easily in most laboratories. HIV antibody assays are now commercially available in various formats. It is necessary to differentiate between HIV-1 and HIV-2 infections as the treatment varies for the two types. HIV-2 is intrinsically resistant to NNRTI drugs.
- Novel assays of immune responses
- Novel approaches to assess viral load and ARV resistance/tropism
- Optimizing selection and procurement of existing paediatric products
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